InTERTesting association between telomerase, mTOR and phytochemicals.

  title={InTERTesting association between telomerase, mTOR and phytochemicals.},
  author={Tabetha Sundin and Patricia Hentosh},
  journal={Expert reviews in molecular medicine},
Telomeres are stretches of repeated DNA sequences located at the ends of chromosomes that are necessary to prevent loss of gene-coding DNA regions during replication. Telomerase - the enzyme responsible for immortalising cancer cells through the addition of telomeric repeats - is active in ~90% of human cancers. Telomerase activity is inhibited by various phytochemicals such as isoprenoids, genistein, curcumin, epigallocatechin-3-gallate, resveratrol and others. Human TERT (telomerase reverse… CONTINUE READING
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