In vivo visualization of the antialbuminuric effects of the angiotensin-converting enzyme inhibitor enalapril.

Abstract

Angiotensin-converting enzyme (ACE) inhibitors are commonly used antiproteinuric drugs. Here we assessed the effect of the ACE inhibitor enalapril on the glomerular sieving coefficient of albumin (GSCA) using intravital multiphoton microscopy. Munich Wistar Frömter (MWF) rats were used as a model of hypertension-related glomerular lesions. Young (9-week-old… (More)
DOI: 10.1124/jpet.114.222125

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