In vivo versus in vitro individual radiosensitivity analysed in healthy donors and in prostate cancer patients with and without severe side effects after radiotherapy.

@article{Brzozowska2012InVV,
  title={In vivo versus in vitro individual radiosensitivity analysed in healthy donors and in prostate cancer patients with and without severe side effects after radiotherapy.},
  author={Kinga Brzozowska and Michael Pinkawa and Prof.Dr.med. Michael J Eble and W. K. M{\"u}ller and Andrzej Wojcik and Ralf Kriehuber and Sabine Ingo Schmitz},
  journal={International journal of radiation biology},
  year={2012},
  volume={88 5},
  pages={
          405-13
        }
}
BACKGROUND A high cellular radiosensitivity may be connected with a risk for development of severe side effects after radiotherapy and indicate cancer susceptibility. Hence, a fast and robust in vitro test is desirable to identify radiosensitive individuals. MATERIALS AND METHODS The study included 25 prostate cancer patients with severe side effects (S) and 25 patients without severe side effects (0) after radiotherapy as well as 23 male healthy age-matched donors. Blood samples were exposed… CONTINUE READING
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