In vivo suppression of visfatin by oral glucose uptake: evidence for a novel incretin-like effect by glucagon-like peptide-1 (GLP-1).

@article{Bala2011InVS,
  title={In vivo suppression of visfatin by oral glucose uptake: evidence for a novel incretin-like effect by glucagon-like peptide-1 (GLP-1).},
  author={Margarita Bala and Josefine T Martin and Andrea Kopp and Frank Hanses and Christa Buechler and Andreas Schaeffler},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2011},
  volume={96 8},
  pages={2493-501}
}
BACKGROUND Visfatin represents an adipokine of the visceral adipose tissue exerting pleiotropic effects. The aim of the study was to characterize the physiological regulation of visfatin release in vivo in healthy, nondiabetic probands and in adipocytes in vitro. SUBJECTS AND METHODS One hundred healthy subjects (64 females and 36 males) underwent an oral glucose tolerance test (75 g). Probands were characterized by anthropometric and laboratory parameters. Fasting and postprandial (1 and 2 h… CONTINUE READING