In vivo studies on the protective role of minocycline against excitotoxicity caused by malonate or N-methyl-d-aspartate.

Abstract

Minocycline has been shown to exert neuroprotection against a wide variety of toxic insults both in vitro and in vivo. However, contradictory results have recently been reported. We now report that minocycline affords no protection against the neurotoxicity caused by malonate or N-methyl-d-aspartate (NMDA). Rats were treated with minocycline (45 mg/kg i.p… (More)

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@article{GoiAllo2005InVS, title={In vivo studies on the protective role of minocycline against excitotoxicity caused by malonate or N-methyl-d-aspartate.}, author={Beatriz Go{\~n}i-Allo and Maria Perp{\'e}tua Oliveira Ramos and Joaqu{\'i}n Jord{\'a}n and Norberto Aguirre}, journal={Experimental neurology}, year={2005}, volume={191 2}, pages={326-30} }