In vivo studies of the cerebral glutamate receptor/NO/cGMP pathway.

@article{Fedele1999InVS,
  title={In vivo studies of the cerebral glutamate receptor/NO/cGMP pathway.},
  author={Ernesto Fedele and Maurizio Raiteri},
  journal={Progress in neurobiology},
  year={1999},
  volume={58 1},
  pages={89-120}
}
Overwhelming evidence indicates that the glutamate/nitric oxide (NO) synthase/soluble guanylyl cyclase system is of primary importance in a variety of physiological and pathological processes of the brain. Most of our knowledge on this neurochemical pathway derives from in vitro and ex vivo studies but the recent improvement of microdialysis techniques combined with extremely sensitive measurements of the amplified end-product cyclic GMP (cGMP) has given new impulses to the investigation of… CONTINUE READING