In vivo studies concerning a pH gradient in human stratum corneum and upper epidermis.

@article{Ohman1994InVS,
  title={In vivo studies concerning a pH gradient in human stratum corneum and upper epidermis.},
  author={Hans Ohman and Anders Vahlquist},
  journal={Acta dermato-venereologica},
  year={1994},
  volume={74 5},
  pages={375-9}
}
Human skin has an acid mantle of pH 4-6, contrasting with the almost neutral pH of the interior body and implying the existence of a pH gradient over the horny layer that might influence a variety of epidermal processes. In an attempt to characterize the pH gradient, we applied a glass electrode to the volar surface of the forearm before and after consecutive strippings with sello-tape. Before stripping, the surface pH (mean +/- SD) was 4.5 +/- 0.2 in men (n = 7) and 5.3 +/- 0.5 in women (n = 7… CONTINUE READING