In vivo self-association of the Drosophila rel-protein dorsal.

  title={In vivo self-association of the Drosophila rel-protein dorsal.},
  author={Shubha Govind and Anne M. Whalen and R. Steward},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={89 17},
The Drosophila morphogen dorsal, KBF1, NF-kappa B, and the proto-oncogene c-rel belong to the rel family of transcription factors whose function is regulated post-translationally by selective nuclear import. In the early Drosophila embryo, dorsal protein is proposed to be retained in the cytoplasm through its interaction with cactus protein. The maternal dorsal group genes constitute a signal transduction pathway, which results in targeting cytoplasmic dorsal protein into the nuclei of the… CONTINUE READING