In vivo selection for Leishmania donovani miniexon genes that increase virulence in Leishmania major.

@article{Zhang2004InVS,
  title={In vivo selection for Leishmania donovani miniexon genes that increase virulence in Leishmania major.},
  author={W W Zhang and Greg Matlashewski},
  journal={Molecular microbiology},
  year={2004},
  volume={54 4},
  pages={1051-62}
}
Different species of Leishmania are responsible for the diverse pathologies associated with leishmaniasis including Leishmania donovani which results in fatal visceral infection and Leishmania major which causes non-fatal cutaneous infection. In an attempt to identify genotypic differences between these related Old World Leishmania species which contribute to their distinct phenotypic characteristics, we have introduced a L. donovani cosmid library into L. major to select for L. donovani… CONTINUE READING
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