In vivo response of mouse liver to gamma-radiation assessed by the comet assay.

@article{Carrera1998InVR,
  title={In vivo response of mouse liver to gamma-radiation assessed by the comet assay.},
  author={Pilar Carrera and Manuel de Miguel and Juan Torres Lopez and Consuelo de la Torre and Matilde H. Navarrete},
  journal={Mutation research},
  year={1998},
  volume={413 1},
  pages={23-31}
}
The alkaline comet assay was used to measure DNA damage induced in liver cells of mice irradiated with gamma-radiation, as well as the repair competency of these cells. A simplified procedure for the isolation of nuclei from cells in solid tissues was developed. This simplified method allows nuclei to be processed into lysis only 5 min after briefly… CONTINUE READING