In vivo reprogramming of immune cells: Technologies for induction of antigen-specific tolerance.

@article{Pearson2017InVR,
  title={In vivo reprogramming of immune cells: Technologies for induction of antigen-specific tolerance.},
  author={Ryan M. Pearson and Liam M. Casey and Kevin R Hughes and Stephen D Miller and Lonnie D Shea},
  journal={Advanced drug delivery reviews},
  year={2017},
  volume={114},
  pages={
          240-255
        }
}
Technologies that induce antigen-specific immune tolerance by mimicking naturally occurring mechanisms have the potential to revolutionize the treatment of many immune-mediated pathologies such as autoimmunity, allograft rejection, and allergy. The immune system intrinsically has central and peripheral tolerance pathways for eliminating or modulating antigen-specific responses, which are being exploited through emerging technologies. Antigen-specific tolerogenic responses have been achieved… CONTINUE READING
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Biomaterials for Engineering Immune Responses

  • Journal of the Indian Institute of Science
  • 2018

Immuno-engineering: The Next Frontier in Therapeutics Delivery.

  • Advanced drug delivery reviews
  • 2017
VIEW 1 EXCERPT
CITES BACKGROUND

References

Publications referenced by this paper.
SHOWING 1-10 OF 165 REFERENCES

Intralymphatic allergen administration renders specific immunotherapy faster and safer: a randomized controlled trial.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 2008
VIEW 15 EXCERPTS
HIGHLY INFLUENTIAL

Advances in islet encapsulation technologies

  • Nature Reviews Drug Discovery
  • 2017
VIEW 3 EXCERPTS

C

D. R. Getts, R. L. Terry, M. T. Getts, C. Deffrasnes, M. Muller
  • van Vreden, T.M. Ashhurst, B. Chami, D. McCarthy, H. Wu, J. Ma, A. Martin, L.D. Shae, P. Witting, G.S. Kansas, J. Kuhn, W. Hafezi, I.L. Campbell, D. Reilly, J. Say, L. Brown, M.Y. White, S.J. Cordwell, S.J. Chadban, E.B. Thorp, S. Bao, S.D.Miller, N.J. King, Therapeutic inflammatory monocyte modulat
  • 2014
VIEW 3 EXCERPTS
HIGHLY INFLUENTIAL