In vivo real-time confocal laser scanning endomicroscopic colonoscopy for the detection and characterization of colorectal neoplasia.

@article{Hurlstone2008InVR,
  title={In vivo real-time confocal laser scanning endomicroscopic colonoscopy for the detection and characterization of colorectal neoplasia.},
  author={David Paul Hurlstone and W Baraza and Sean Brown and Melissa Thomson and Nick Tiffin and Simon S. Cross},
  journal={The British journal of surgery},
  year={2008},
  volume={95 5},
  pages={636-45}
}
BACKGROUND Conventional colonoscopy has a significant false-negative rate for intraepithelial neoplasia. Chromoendoscopy increases sensitivity but lacks specificity. The aim was to assess prospectively the clinical applicability and predictive power of the EC3870CIFK confocal laser endomicroscope (CLE) for the in vivo diagnosis of intraepithelial neoplasia during colonoscopy. METHODS Lesions were identified using chromoscopy followed by CLE imaging and graded according to vascular and… CONTINUE READING

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