In vivo quantitative assessment of catheter patency in rats.

  title={In vivo quantitative assessment of catheter patency in rats.},
  author={Jun J. Yang and Jean-Michel I. Maarek and Daniel P. Holschneider},
  journal={Laboratory animals},
  volume={39 3},
Formation of fibrin sleeves around catheter tips is a central factor in catheter failure during chronic implantation, and such tissue growth can occur despite administration of anticoagulants. We developed a novel method for monitoring catheter patency. This method recognizes the progressive nature of catheter occlusion, and tracks this process over time through measurement of changes in catheter resistance to a standardized 1 mL bolus infusion from a pressurized reservoir. Two indirect… CONTINUE READING


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