In vivo quantification of myocardial muscarinic receptors in heart transplant patients.


BACKGROUND Decreased myocardial adenylate cyclase activity in response to guanine nucleotide stimulation has been recently demonstrated in denervated myocardium of transplant patients, suggesting that changes in left ventricular muscarinic receptors may occur. METHODS AND RESULTS The concentration and affinity constants of myocardial muscarinic receptors… (More)


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