In vivo proton T1 relaxation times of mouse myocardial metabolites at 9.4 T.

@article{Bakermans2015InVP,
  title={In vivo proton T1 relaxation times of mouse myocardial metabolites at 9.4 T.},
  author={Adrianus J. Bakermans and Desiree Abdurrachim and Tom R Geraedts and Sander M. Houten and Klaas Nicolay and J. J. Prompers},
  journal={Magnetic resonance in medicine},
  year={2015},
  volume={73 6},
  pages={2069-74}
}
PURPOSE Proton magnetic resonance spectroscopy ((1) H-MRS) for quantitative in vivo assessment of mouse myocardial metabolism requires accurate acquisition timing to minimize motion artifacts and corrections for T1 -dependent partial saturation effects. In this study, mouse myocardial water and metabolite T1 relaxation time constants were quantified. METHODS Cardiac-triggered and respiratory-gated PRESS-localized (1) H-MRS was employed at 9.4 T to acquire signal from a 4-µL voxel in the… CONTINUE READING
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