In vivo production of interleukin-10 by non-T cells in rheumatoid arthritis, Sjögren's syndrome, and systemic lupus erythematosus. A potential mechanism of B lymphocyte hyperactivity and autoimmunity.

Abstract

OBJECTIVE Interleukin-10 (IL-10) is a potent stimulator of B lymphocytes in vitro. In vivo dysregulation of IL-10 gene expression was therefore analyzed in patients with rheumatoid arthritis (RA), primary Sjögren's syndrome (SS), and systemic lupus erythematosus (SLE). METHODS Spontaneous production of IL-10 by peripheral blood mononuclear cells was… (More)

Topics

Cite this paper

@article{Llorente1994InVP, title={In vivo production of interleukin-10 by non-T cells in rheumatoid arthritis, Sj{\"o}gren's syndrome, and systemic lupus erythematosus. A potential mechanism of B lymphocyte hyperactivity and autoimmunity.}, author={Leopoldo Llorente and Yvonne Richaud-Pat{\'i}n and Renato Fior and Jorge Alcocer-Varela and Jan W Wijdenes and B M Fourrier and Pierce Galanaud and Dama Emilie}, journal={Arthritis and rheumatism}, year={1994}, volume={37 11}, pages={1647-55} }