In vivo production of interleukin-10 by malignant cells in AIDS lymphomas.

@article{Emilie1992InVP,
  title={In vivo production of interleukin-10 by malignant cells in AIDS lymphomas.},
  author={Dominique Emilie and Robert Touitou and Marilyn Raphael and M. Peuchmaur and O Devergnee and Delphine R{\'e}a and J Coumbraras and M C Crevon and Louis M. Edelman and Ir{\`e}ne Joab},
  journal={European journal of immunology},
  year={1992},
  volume={22 11},
  pages={
          2937-42
        }
}
Expression of the interleukin (IL)-10/BCRF1 gene was studied by in situ hybridization in tissue samples from acquired immunodeficiency syndrome (AIDS) lymphomas using a BCRF1 probe which also recognizes the human IL-10 sequence. Hybridization was detected in 8 out of 15 lymphomas. In contrast, the IL-10/BCRF1 gene expression was detected in only 1 out of 11 lymphomas from human immunodeficiency virus (HIV)-seronegative patients (p = 0.05). In AIDS lymphomas, the number of cells labeled with a… CONTINUE READING

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