In vivo preservation of steroid specificity in CWR22 xenografts having a mutated androgen receptor.

Abstract

BACKGROUND In vitro studies of CWR22 tumor cells lack steroid specificity. We sought to determine if CWR22 xenografts also lack steroid specificity. METHODS We injected castrated nude mice with CWR22 tumor cells (6 x 10(6) cells) and implanted Alzet osmotic pumps that delivered approximately 1 mg steroid/kg body weight/day. RESULTS Serum PSA levels were… (More)

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Cite this paper

@article{Shao2003InVP, title={In vivo preservation of steroid specificity in CWR22 xenografts having a mutated androgen receptor.}, author={Tsang C Shao and Huiling Li and Wael Eid and Michael Ittmann and Emmanual Unni and Glenn R. Cunningham}, journal={The Prostate}, year={2003}, volume={57 1}, pages={1-7} }