In vivo phosphoenolpyruvate carboxykinase promoter mapping identifies disrupted hormonal synergism as a target of inflammation during sepsis in mice.

@article{Chichelnitskiy2009InVP,
  title={In vivo phosphoenolpyruvate carboxykinase promoter mapping identifies disrupted hormonal synergism as a target of inflammation during sepsis in mice.},
  author={Evgeny Chichelnitskiy and Alexandros Vegiopoulos and Mauricio Berriel D{\'i}az and Anja S. Ziegler and Anna Kleiman and Alexander Rauch and Jan P Tuckermann and Stephan Herzig},
  journal={Hepatology},
  year={2009},
  volume={50 6},
  pages={1963-71}
}
UNLABELLED In mammals, proper maintenance of blood glucose levels within narrow limits is one of the most critical prerequisites for healthy energy homeostasis and body function. Consequently, hyper- and hypoglycemia represent hallmarks of severe metabolic pathologies, including type II diabetes and acute sepsis, respectively. Although the liver plays a crucial role in the control of systemic glucose homeostasis, the molecular mechanisms of aberrant hepatic glucose regulation under metabolic… CONTINUE READING

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