In vivo pharmacokinetics of hesperidin are affected by treatment with glucosidase-like BglA protein isolated from yeasts.

@article{Li2008InVP,
  title={In vivo pharmacokinetics of hesperidin are affected by treatment with glucosidase-like BglA protein isolated from yeasts.},
  author={Yong-mei Li and Xiao-mian Li and Guangming Li and W. Du and J. Zhang and Wei-Xia Li and Jiansheng Xu and M. Hu and Ze Zhu},
  journal={Journal of agricultural and food chemistry},
  year={2008},
  volume={56 14},
  pages={
          5550-7
        }
}
Hesperidin is an abundant flavanone glycoside in citrus fruits and has been reported to possess a wide range of biological activities. However, hesperidin has poor bioavailability. Here, we tested the hypothesis that hesperetin found in chenpi will have a better bioavailability than hesperidin and that treatment of hesperidin with the glucosidase-like yeast Bg1A protein will increase its bioavailability. The results indicate that hesperidin in pure or extract form is hydrolyzed by BglA protein… Expand
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