In vivo performance of a novel silk fibroin scaffold for partial meniscal replacement in a sheep model

@inproceedings{Gruchenberg2014InVP,
  title={In vivo performance of a novel silk fibroin scaffold for partial meniscal replacement in a sheep model},
  author={Katharina Gruchenberg and Anita Ignatius and Benedikt Friemert and Falk von Luebken and Nick Skaer and Kris Gellynck and Oliver C Kessler and Lutz D{\"u}rselen},
  booktitle={Knee Surgery, Sports Traumatology, Arthroscopy},
  year={2014}
}
Due to the negative effects of meniscectomy, there is a need for an adequate material to replace damaged meniscal tissue. To date, no material tested has been able to replace the meniscus sufficiently. Therefore, a new silk fibroin scaffold was investigated in an in vivo sheep model. Partial meniscectomy was carried out to the medial meniscus of 28 sheep, and a scaffold was implanted in 19 menisci (3-month scaffold group, n = 9; 6-month scaffold group, n = 10). In 9 sheep, the defect remained… CONTINUE READING