In vivo parasitological measures of artemisinin susceptibility.

@article{Stepniewska2010InVP,
  title={In vivo parasitological measures of artemisinin susceptibility.},
  author={K. Stepniewska and E. Ashley and Sue J Lee and N. Anstey and K. Barnes and T. Binh and U. d’Alessandro and N. Day and P. D. de Vries and G. Dorsey and J. Guthmann and M. Mayxay and P. Newton and P. Olliaro and L. Osorio and R. Price and M. Rowland and F. Smithuis and W. Taylor and F. Nosten and N. White},
  journal={The Journal of infectious diseases},
  year={2010},
  volume={201 4},
  pages={
          570-9
        }
}
Parasite clearance data from 18,699 patients with falciparum malaria treated with an artemisinin derivative in areas of low (n=14,539), moderate (n=2077), and high (n=2083) levels of malaria transmission across the world were analyzed to determine the factors that affect clearance rates and identify a simple in vivo screening measure for artemisinin resistance. The main factor affecting parasite clearance time was parasite density on admission. Clearance rates were faster in high-transmission… Expand

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