In vivo opioid receptor occupation in the rat brain following exercise.

@article{Sforzo1986InVO,
  title={In vivo opioid receptor occupation in the rat brain following exercise.},
  author={Gary A. Sforzo and Thomas F Seeger and Candace B. Pert and Agu Pert and Charles O. Dotson},
  journal={Medicine and science in sports and exercise},
  year={1986},
  volume={18 4},
  pages={380-4}
}
The effects of prolonged swim-stress (2 h and 1 h) upon brain opioid receptor binding of tritiated [3H]diprenorphine were investigated in male Sprague-Dawley rats. This was accomplished by injecting the label intravenously immediately following the swim, then allowing 20 min for tracer washout from non-specific binding sites, sacrificing the animal, dissecting the brain into several discrete areas (medulla-pons, mid-brain, mesolimbic, caudate, thalamus, and hypothalamus), and subsequently… CONTINUE READING

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