In vivo oocyte developmental competence is reduced in lean but not in obese superovulated dairy cows after intraovarian administration of IGF1.

@article{Velzquez2011InVO,
  title={In vivo oocyte developmental competence is reduced in lean but not in obese superovulated dairy cows after intraovarian administration of IGF1.},
  author={Miguel Abraham Vel{\'a}zquez and Klaus-Gerd Hadeler and Doris Herrmann and Wilfried A Kues and Susanne E Ulbrich and Heinrich H. D. Meyer and Beno{\^i}t R{\'e}my and J P Beckers and Helga Sauerwein and Heiner Niemann},
  journal={Reproduction},
  year={2011},
  volume={142 1},
  pages={41-52}
}
The present study investigated the role of IGF1 in lactating lean and non-lactating obese dairy cows by injecting 1 μg IGF1 into the ovaries prior to superovulation. This amount of IGF1 has been linked with pregnancy loss in women with the polycystic ovary syndrome (PCOS) and was associated with impaired bovine oocyte competence in vitro. Transcript… CONTINUE READING