In vivo neuroprotection by a creatine-derived compound: phosphocreatine-Mg-complex acetate.

@article{Perasso2009InVN,
  title={In vivo neuroprotection by a creatine-derived compound: phosphocreatine-Mg-complex acetate.},
  author={Luisa Perasso and Enrico Adriano and Piero Ruggeri and Sergey V Burov and Carlo Gandolfo and Maurizio Balestrino},
  journal={Brain research},
  year={2009},
  volume={1285},
  pages={158-63}
}
Phosphocreatine-Mg-complex acetate (PCr-Mg-CPLX) is a creatine-derived compound that in previous in vitro research was able to increase neuronal creatine independently of the creatine transporter, thus providing hope to cure the hereditary syndrome of creatine transporter deficiency. In previous research we showed that it reproduces in vitro the known neuroprotective effect of creatine against anoxic damage. In the present paper we investigated if PCr-Mg-CPLX reproduces this neuroprotective… CONTINUE READING
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