In vivo near-infrared spectroscopy and magnetic resonance imaging monitoring of tumor response to combretastatin A-4-phosphate correlated with therapeutic outcome.

@article{Zhao2011InVN,
  title={In vivo near-infrared spectroscopy and magnetic resonance imaging monitoring of tumor response to combretastatin A-4-phosphate correlated with therapeutic outcome.},
  author={Dawen Zhao and Cheng-Hui Chang and Jae Gon Kim and Hanli Liu and Ralph P. Mason},
  journal={International journal of radiation oncology, biology, physics},
  year={2011},
  volume={80 2},
  pages={574-81}
}
PURPOSE To develop a combination treatment consisting of combretastatin A-4-phosphate (CA4P) with radiation based on tumor oxygenation status. METHODS AND MATERIALS In vivo near-infrared spectroscopy (NIRS) and diffusion-weighted (DW) magnetic resonance imaging (MRI) were applied to noninvasively monitor changes in tumor blood oxygenation and necrosis induced by CA4P (30 mg/kg) in rat mammary 13762NF adenocarcinoma, and the evidence was used to optimize combinations of CA4P and radiation… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 22 references

Diffusion magnetic resonance imaging: a biomarker for treatment response in oncology.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology • 2007

Tumor physiologic response to combretastatin A4 phosphate assessed by MRI.

International journal of radiation oncology, biology, physics • 2005
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