In vivo near-infrared fluorescence imaging of integrin alphavbeta3 in brain tumor xenografts. - Semantic Scholar

Abstract

Noninvasive visualization of cell adhesion molecule alpha(v)beta(3) integrin expression in vivo has been well studied by using the radionuclide imaging modalities in various preclinical tumor models. A literature survey indicated no previous use of cyanine dyes as contrast agents for in vivo optical detection of tumor integrin. Herein, we report the… (More)

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