In vivo natriuretic peptide reporter assay identifies chemical modifiers of hypertrophic cardiomyopathy signalling.

Abstract

AIMS Despite increased understanding of the fundamental biology regulating cardiomyocyte hypertrophy and heart failure, it has been challenging to find novel chemical or genetic modifiers of these pathways. Traditional cell-based methods do not model the complexity of an intact cardiovascular system and mammalian models are not readily adaptable to chemical… (More)
DOI: 10.1093/cvr/cvr350

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Cite this paper

@article{Becker2012InVN, title={In vivo natriuretic peptide reporter assay identifies chemical modifiers of hypertrophic cardiomyopathy signalling.}, author={Jason R. Becker and Tamara Y Robinson and Chetana Sachidanandan and Amy E. Kelly and Shannon Michael Coy and Randall T. Peterson and Calum A MacRae}, journal={Cardiovascular research}, year={2012}, volume={93 3}, pages={463-70} }