In vivo modulation of the allogeneic immune response by human fetal kidneys: the role of cytokines, chemokines, and cytolytic effector molecules.

@article{Dekel2000InVM,
  title={In vivo modulation of the allogeneic immune response by human fetal kidneys: the role of cytokines, chemokines, and cytolytic effector molecules.},
  author={Benjamin Dekel and Hadar Marcus and B H Herzel and Wulf Otto Boecher and Justen Howard Passwell and Yair Reisner},
  journal={Transplantation},
  year={2000},
  volume={69 7},
  pages={
          1470-8
        }
}
BACKGROUND We have recently demonstrated that human fetal renal tissue, implanted under the kidney capsule of severe immunodeficient rats, escapes early destruction by intraperitoneal infusion of allogeneic human peripheral blood mononuclear cells, compared with the rapid rejection of implants of human adult kidney tissue. Variable amounts of human mononuclear infiltrates were seen in the transplanted fetal kidney, however, prolonged survival of the fetal tissue (maintenance of graft… CONTINUE READING
BETA

Similar Papers

Loading similar papers…