In vivo modulation of 5-hydroxytryptamine release in mouse prefrontal cortex by local 5-HT(2A) receptors: effect of antipsychotic drugs.

@article{Bortolozzi2003InVM,
  title={In vivo modulation of 5-hydroxytryptamine release in mouse prefrontal cortex by local 5-HT(2A) receptors: effect of antipsychotic drugs.},
  author={Anal{\'i}a Bortolozzi and Merc{\`e} Amarg{\'o}s-Bosch and Albert Adell and Llorenç D{\'i}az-Mataix and Jordi Serrats and Sebasti{\`a} Pons and Francesc Casa{\~n}as Artigas},
  journal={The European journal of neuroscience},
  year={2003},
  volume={18 5},
  pages={
          1235-46
        }
}
In the rat, postsynaptic 5-hydroxytryptamine2A receptors medial prefrontal cortex control the activity of the serotonergic system through changes in the activity of pyramidal neurons projecting to the dorsal raphe nucleus. Here we extend these observations to mouse brain. The prefrontal cortex expresses abundant 5- hydroxytryptamine2A receptors, as assessed by immunohistochemistry, Western blots and in situ hybridization procedures. The application of the 5-hydroxytryptamine2A/2C agonist DOI… CONTINUE READING
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