In vivo metabolism of N-phenyl-N′-(3,5-dimethylpyrazole-4-yl) thiourea in rats

Abstract

Thiourea derivatives have been shown to posses several biological activities. Therefore a series of N-substituted-N′-(3,5-di/1,3,5-trimethylpyrazole-4-yl)thioureas were synthesized and the antitubercular and anticonvulsant activities were studied. Among the new compounds, N-phenyl-N′-(3,5-dimethylpyrazole-4-yl)thiourea (S) was demonstrated to have… (More)
DOI: 10.1007/BF03220179

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