In vivo measurement of brain glucose transport and metabolism employing glucose- -11C.

@article{Raichle1975InVM,
  title={In vivo measurement of brain glucose transport and metabolism employing glucose- -11C.},
  author={Marcus E. Raichle and Kyle Larson and Michael E. Phelps and Robert L. Grubb and Michael J. Welch and Michel M. Ter-Pogossian},
  journal={The American journal of physiology},
  year={1975},
  volume={228 6},
  pages={1936-48}
}
The radiopharmaceutical glucose--11C was used in vivo measurement of brain-glucose transport kinetics and metabolism in the rhesus monkey. Radiotracer was injected intravenously as a bolus. Radioactivity was continuously recorded from the head and from the arterial blood via an indwelling peripheral artery catheter for a collectionperiod of 2-3 min. To correct the reading obtained from the head for radioactivitycontained in blood, a second intravenous injection of the vascular tracer -15O… CONTINUE READING