In vivo meal model for the evaluation of agents which affect the absorption of triglyceride and cholesterol.

@article{Comai1980InVM,
  title={In vivo meal model for the evaluation of agents which affect the absorption of triglyceride and cholesterol.},
  author={Karen Comai and Ann C. Sullivan},
  journal={Biochemical pharmacology},
  year={1980},
  volume={29 11},
  pages={
          1475-82
        }
}
3 Citations
Gastric Emptying in Rats following Administration of a Range of Different Fats Measured as Acetaminophen Concentration in Plasma
TLDR
The gastric emptying of fat was not influenced by fatty acid composition and triacylglycerol structure of the fats administered, and similar weights of fat were administered.
Effect of phenoxybenzamine on development of adipose tissue in lean and obese Zucker rats.
TLDR
This study shows that despite severe restrictions in fat cell proliferation during the rapid-growth phase of the obese Zucker rat, the mechanisms for cellular proliferation and fat deposition remain intact.

References

SHOWING 1-10 OF 21 REFERENCES
The effect of a nonabsorbable lipid, sucrose polyester, on the absorption of dietary cholesterol by the rat.
TLDR
The absorption of cholesterol from diets containing various proportions of triglycerides and an unabsorbable fat, sucrose polyester (SPE), was determined in rats and cholesterol was found to be equally soluble in triolein or SPE.
Absorption of dietary fats by the rat in cholestyramine-induced steatorrhea.
TLDR
Cholestyramine, a bile acid-sequestering resin, impaired fat absorption in weanling rats fed a diet containing 15% corn oil, and net retention of the medium-chain fatty acids and lino- leic acid was high even with marked Steatorrhea, whereas the long-chain saturated fatty acidsand oleic acid were poorly absorbed.
Dietary influences on gastric emptying of carbohydrate versus fat in the rat.
TLDR
The kind and form of carbohydrate in the meals and the ease of its extraction with water appear to be important factors governing the degree to which carbohydrates is preferentially emptied from the stomach.
Absorbability by rats of compounds containing from one to eight ester groups.
TLDR
Differences in absorbability are related to the activity and specificity of the lipo- lytic enzymes in the lumen of the intestinal tract.
QUANTITATIVE ISOLATION AND GAS--LIQUID CHROMATOGRAPHIC ANALYSIS OF TOTAL DIETARY AND FECAL NEUTRAL STEROIDS.
TLDR
The sensitivity of the method is such that I-g fecal aliquots containing as little as 25 pg of mixed neutral steroids can be analyzed accurately, but the procedure lends itself well to preparative scale work for more definitive study of individual neutral steroids.
Use of labelled triolein, vitamin A, and D-xylose in the diagnosis of malabsorption 1
TLDR
The type of results given by a group of test procedures used in the study of small intestinal dysfunction show patterns of results which are useful in differentiating idiopathic from secondary steatorrhoea, since patients with secondary malabsorption often handle one or more of these test substances normally.
Effect of Non-Ionic Detergents on the Absorption of Fat and α-Tocopherol in the Rat
Malabsorption of fat and α-tocopherol was induced in rats by feeding cholestyramine and the effect of Tween 80 and Pluronic F 68 was assessed. Tween 80 did not influence the malabsorption of fat or α-
...
...