In vivo localization of diglycylcysteine-bearing synthetic peptides by nuclear imaging of oxotechnetate transchelation.

Abstract

A phenomenon of in vivo transchelation of oxotechnetate from a complex with glucoheptonic acid to synthetic peptides bearing oxotechnetate-binding motifs and a technique for in vivo visualization of these peptides are described. Using two model peptides bearing two tandem diglycylcysteine (GGC) motifs (P1) or three GGC motifs (P2), we demonstrated that: (i… (More)

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@article{Bogdanov1997InVL, title={In vivo localization of diglycylcysteine-bearing synthetic peptides by nuclear imaging of oxotechnetate transchelation.}, author={A. V. Bogdanov and P Petherick and Edgardo M Marecos and Ralf Weissleder}, journal={Nuclear medicine and biology}, year={1997}, volume={24 8}, pages={739-42} }