In vivo kinetics of intestinal absorption of riboflavin in rats.

@article{Feder1991InVK,
  title={In vivo kinetics of intestinal absorption of riboflavin in rats.},
  author={Stuart Feder and Hannelore Daniel and Gertrud Rehner},
  journal={The Journal of nutrition},
  year={1991},
  volume={121 1},
  pages={
          72-9
        }
}
To investigate absorption kinetics of riboflavin under in vivo conditions, with blood and lymph circulation intact, the small intestine of anesthetized rats was perfused with [14C]riboflavin in a concentration range between 0.31 and 10.00 mumol/L. Apart from the uptake of riboflavin from the perfusate, passage of the vitamin into the portal (vena portae) and peripheral (vena femoralis) blood was determined. The absorption proved to be a dual process: at low substrate concentrations (less than 2… CONTINUE READING
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