In vivo intervertebral disc regeneration using stem cell-derived chondroprogenitors.

@article{Sheikh2009InVI,
  title={In vivo intervertebral disc regeneration using stem cell-derived chondroprogenitors.},
  author={Hormoz Sheikh and Karen Zakharian and Ramiro Perez De La Torre and Christopher Facek and Adrian Amelio Vasquez and G Rasul Chaudhry and David M. Svinarich and Mick J. Perez-Cruet},
  journal={Journal of neurosurgery. Spine},
  year={2009},
  volume={10 3},
  pages={265-72}
}
OBJECT There is currently no biologic therapy to repair or restore a degenerated intervertebral disc. A potential solution may rest with embryonic stem cells (ESCs), which have a potential to grow indefinitely and differentiate into a variety of cell types in vitro. Prior studies have shown that ESCs can be encouraged to differentiate toward specific cell lineages by culture in selective media and specific growth environment. Among these lineages, there are cells capable of potentially… CONTINUE READING