In vivo inhibition of angiogenesis and growth of the human U-87 malignant glial tumor by treatment with an antibody against basic fibroblast growth factor.

@article{Stan1995InVI,
  title={In vivo inhibition of angiogenesis and growth of the human U-87 malignant glial tumor by treatment with an antibody against basic fibroblast growth factor.},
  author={Alexandru Constantin Stan and M. N. Nemati and Torsten Pietsch and Gerhard F. Walter and Hermann Dietz},
  journal={Journal of neurosurgery},
  year={1995},
  volume={82 6},
  pages={1044-52}
}
The effectiveness of in vivo suppression of neovascularization and growth of malignant glial tumors by in situ administration of an antibody directed against basic fibroblast growth factor (bFGF), a strong mitogen for cells of mesodermal origin, was tested. One hundred fifty congenitally athymic nude rats (han rnu/rnu) were implanted intracerebrally with U… CONTINUE READING