In vivo induction of regulatory T cells promotes allergen tolerance and suppresses allergic contact dermatitis.

Abstract

Allergic contact dermatitis (ACD) is a common T-cell mediated inflammatory skin condition, characterized by an intensely pruritic rash at the site of contact with allergens like poison ivy or nickel. Current clinical treatments use topical corticosteroids, which broadly and transiently suppress inflammation and symptoms of ACD, but fail to address the… (More)
DOI: 10.1016/j.jconrel.2017.07.006

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