In vivo imaging systems (IVIS) detection of a neuro-invasive encephalitic virus.

@article{Poussard2012InVI,
  title={In vivo imaging systems (IVIS) detection of a neuro-invasive encephalitic virus.},
  author={Allison L. Poussard and Michael V. Patterson and K. H. Taylor and Alexey V. Seregin and Jeanon N. Smith and Jennifer K. Smith and Milagros Salazar and Slobodan Paessler},
  journal={Journal of visualized experiments : JoVE},
  year={2012},
  volume={70},
  pages={
          e4429
        }
}
Modern advancements in imaging technology encourage further development and refinement in the way viral research is accomplished. Initially proposed by Russel and Burch in Hume's 3Rs (replacement, reduction, refinement), the utilization of animal models in scientific research is under constant pressure to identify new methodologies to reduce animal usage while improving scientific accuracy and speed. A major challenge to Hume's principals however, is how to ensure the studies are statistically… CONTINUE READING