In vivo imaging of transplanted hematopoietic stem and progenitor cells in mouse calvarium bone marrow

@article{Celso2011InVI,
  title={In vivo imaging of transplanted hematopoietic stem and progenitor cells in mouse calvarium bone marrow},
  author={Cristina Lo Celso and Charles P. Lin and David T Scadden},
  journal={Nature Protocols},
  year={2011},
  volume={6},
  pages={1-14}
}
In vivo imaging of transplanted hematopoietic stem and progenitor cells (HSPCs) was developed to investigate the relationship between HSPCs and components of their microenvironment in the bone marrow. In particular, it allows a direct observation of the behavior of hematopoietic cells during the first few days after transplantation, when the critical events in homing and early engraftment are occurring. By directly imaging these events in living animals, this method permits a detailed… CONTINUE READING
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Haematopoietic stem cells depend on Galpha ( s )mediated signalling to engraft bone marrow

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