In vivo imaging of synaptic function in the central nervous system: I. Movement disorders and dementia.

@article{Nikolaus2009InVI,
  title={In vivo imaging of synaptic function in the central nervous system: I. Movement disorders and dementia.},
  author={Susanne Nikolaus and Christina Antke and Hans-Wilhelm M{\"u}ller},
  journal={Behavioural brain research},
  year={2009},
  volume={204 1},
  pages={1-31}
}
This review gives an overview of those in vivo imaging studies on synaptic neurotransmission, which so far have been performed on patients with movement disorders and/or dementia. Thereby, the focus is on disease-related deficiencies within the functional entity of the dopaminergic, serotonergic, cholinergic, glutamatergic, GABAergic or opioid synapse. In vivo investigations have yielded highly consistent results on the dysfunction of synaptic constituents in the majority of diseases covered by… CONTINUE READING