In vivo imaging of specialized bone marrow endothelial microdomains for tumour engraftment.

Abstract

The organization of cellular niches is known to have a key role in regulating normal stem cell differentiation and regeneration, but relatively little is known about the architecture of microenvironments that support malignant metastasis. Using dynamic in vivo confocal imaging, here we show that murine bone marrow contains unique anatomic regions defined by… (More)
DOI: 10.1038/nature03703

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@article{Sipkins2005InVI, title={In vivo imaging of specialized bone marrow endothelial microdomains for tumour engraftment.}, author={Dorothy A. Sipkins and Xunbin Wei and Juwell W. Wu and Judith M. Runnels and Daniel C C{\^o}t{\'e} and Terry K. Means and Andrew D Luster and David T Scadden and Charles Lin}, journal={Nature}, year={2005}, volume={435 7044}, pages={969-73} }