In vivo imaging of mitochondrial function in methamphetamine-treated rats

@article{Shiba2011InVI,
  title={In vivo imaging of mitochondrial function in methamphetamine-treated rats},
  author={Takeshi Shiba and Mayumi Yamato and Wataru Kudo and Toshiaki Watanabe and Hideo Utsumi and Ken-ichi Yamada},
  journal={NeuroImage},
  year={2011},
  volume={57 3},
  pages={866-72}
}
Abuse of the powerfully addictive psychostimulant, methamphetamine, occurs worldwide. Recent studies have suggested that methamphetamine-induced dopaminergic neurotoxicity is related to oxidative stress. In response to nerve activation, the mitochondrial respiratory chain is rapidly activated. The enhancement of mitochondrial respiratory chain activation may induce oxidative stress in the brain. However, there is little experimental evidence regarding the mitochondrial function after… CONTINUE READING
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