In vivo imaging of juxtaglomerular neuron turnover in the mouse olfactory bulb.

@article{Mizrahi2006InVI,
  title={In vivo imaging of juxtaglomerular neuron turnover in the mouse olfactory bulb.},
  author={Adi Mizrahi and Jing Hua Lu and Ryan P. Irving and Guoping Feng and Lawrence Charles Katz},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2006},
  volume={103 6},
  pages={
          1912-7
        }
}
As a consequence of adult neurogenesis, the olfactory bulb (OB) receives a continuous influx of newborn neurons well into adulthood. However, their rates of generation and turnover, the factors controlling their survival, and how newborn neurons intercalate into adult circuits are largely unknown. To visualize the dynamics of adult neurogenesis, we produced a line of transgenic mice expressing GFP in approximately 70% of juxtaglomerular neurons (JGNs), a population that undergoes adult… CONTINUE READING
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N EU RO SC IE N CE A. 0 -2μm -4μm -6μm Pr oj ec tio n B. Day 0 Day 30 Figure S1 Figure S2 GFP+ BrdU+ Merge 1 day 30 day Time after BrdU injection

  • G. Feng, J. Gross, J. Lu
  • PNAS February
  • 2006
1 Excerpt

www.pnas.org cgi doi 10.1073

  • Q. T. Nguyen, J. R. Sanes, J. W. Lichtman
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