In vivo imaging of human cone photoreceptor inner segments.

  title={In vivo imaging of human cone photoreceptor inner segments.},
  author={Drew H Scoles and Yusufu Sulai and Christopher S. Langlo and Gerald Allen Fishman and Christine A. Curcio and Joseph Carroll and Alfredo Dubra},
  journal={Investigative ophthalmology & visual science},
  volume={55 7},
PURPOSE An often overlooked prerequisite to cone photoreceptor gene therapy development is residual photoreceptor structure that can be rescued. While advances in adaptive optics (AO) retinal imaging have recently enabled direct visualization of individual cone and rod photoreceptors in the living human retina, these techniques largely detect strongly directionally-backscattered (waveguided) light from normal intact photoreceptors. This represents a major limitation in using existing AO imaging… CONTINUE READING