In vivo imaging, tracking, and targeting of cancer stem cells.

@article{Vlashi2009InVI,
  title={In vivo imaging, tracking, and targeting of cancer stem cells.},
  author={Erina Vlashi and Kwanghee Kim and Chann Lagadec and Lorenza Della Donna and J Tyson McDonald and Mohammad Hosein Eghbali and James W. Sayre and Encrico Stefani and William Mcbride and Frank Pajonk},
  journal={Journal of the National Cancer Institute},
  year={2009},
  volume={101 5},
  pages={
          350-9
        }
}
BACKGROUND There is increasing evidence that solid cancers contain cancer-initiating cells (CICs) that are capable of regenerating a tumor that has been surgically removed and/or treated with chemotherapy and/or radiation therapy. Currently, cell surface markers, like CD133 or CD44, are used to identify CICs in vitro; however, these markers cannot be used to identify and track CICs in vivo. The 26S proteasome is the main regulator of many processes within a proliferating cell, and its activity… CONTINUE READING

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