In vivo genetic cell lineage tracing reveals that oviductal secretory cells self-renew and give rise to ciliated cells.

@article{Ghosh2017InVG,
  title={In vivo genetic cell lineage tracing reveals that oviductal secretory cells self-renew and give rise to ciliated cells.},
  author={Arnab Ghosh and Shafiq M. Syed and Pradeep S Tanwar},
  journal={Development},
  year={2017},
  volume={144 17},
  pages={
          3031-3041
        }
}
The epithelial lining of the fallopian tube is vital for fertility, providing nutrition to gametes and facilitating their transport. It is composed of two major cell types: secretory cells and ciliated cells. Interestingly, human ovarian cancer precursor lesions primarily consist of secretory cells. It is unclear why secretory cells are the dominant cell type in these lesions. Additionally, the underlying mechanisms governing fallopian tube epithelial homoeostasis are unknown. In the present… CONTINUE READING
BETA
13
Twitter Mentions

Figures and Topics from this paper.

Explore Further: Topics Discussed in This Paper

References

Publications referenced by this paper.
SHOWING 1-10 OF 55 REFERENCES

The Notch and Wnt pathways D

M. Kessler, K. Hoffmann, +7 authors J Sehouli
  • 2015
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

The Oviducal Epithelium of the Mouse.

  • Journal of anatomy
VIEW 5 EXCERPTS
HIGHLY INFLUENTIAL

Estrogen receptor α is required for oviductal transport of embryos.

  • FASEB journal : official publication of the Federation of American Societies for Experimental Biology
  • 2017
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Similar Papers

Loading similar papers…