In vivo generation of human dendritic cell subsets by Flt3 ligand.

@article{Maraskovsky2000InVG,
  title={In vivo generation of human dendritic cell subsets by Flt3 ligand.},
  author={Eugene Maraskovsky and Elizabeth Daro and Emeric Roux and Mark C. Teepe and Charles R. Maliszewski and J. A. F. van der Hoek and Dania Caron and M E Lebsack and Hilary J. Mckenna},
  journal={Blood},
  year={2000},
  volume={96 3},
  pages={878-84}
}
Dendritic cells (DCs) represent a family of ontogenically distinct leukocytes involved in immune response regulation. The ability of DCs to stimulate T-cell immunity has led to their use as vectors for immunotherapy vaccines. However, it is unclear whether and to what degree in vitro-generated DCs are representative of DCs that develop in vivo. Treatment of… CONTINUE READING