In vivo functional analysis of the mouse estrogen receptor gene promoter: a transgenic mouse model to study tissue-specific and developmental regulation of estrogen receptor gene transcription.

@article{Cicatiello1995InVF,
  title={In vivo functional analysis of the mouse estrogen receptor gene promoter: a transgenic mouse model to study tissue-specific and developmental regulation of estrogen receptor gene transcription.},
  author={Luigi Cicatiello and Gilda Cobellis and Raffaele Addeo and Moshe Papa and Lucia Altucci and Vincenzo Sica and Francesco Bresciani and Marianne Lemeur and V. Lalith Kumar and Pierre Chambon},
  journal={Molecular endocrinology},
  year={1995},
  volume={9 8},
  pages={
          1077-90
        }
}
Understanding the molecular and morphological basis of estrogen responsiveness in the various tissues and organs that make up an adult organism and its onset during ontogenesis requires identification of the genetic controls that determine timed expression of the estrogen receptor (ER) gene in multiple cell types. With this goal in mind, we describe here the results of the functional analysis of the mouse (m) ER gene promoter, carried out in vivo in transgenic mice. The mER gene promoter was… CONTINUE READING