In vivo from Normal Phenotype in Three Dimensional Cultures and Cancer Cells, Inhibits Growth, and Distinguishes Malignant Integrin Inhibitory Antibody Induces Apoptosis of Breast

Abstract

Current therapeutic approaches to cancer are designed to target molecules that contribute to malignant behavior but leave normal tissues intact. B1 integrin is a candidate target well known for mediating cell-extracellular matrix (ECM) interactions that influence diverse cellular functions; its aberrant expression has been implicated in breast cancer… (More)
DOI: 10.1158/0008-5472.CAN-05-3071

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